California Veterinary Specialists continues to work with medical industry partners to help create new therapies for the treatment of our companion animal family members. We have recently launched a Phase II double blind placebo controlled clinical trial targeting canine lipomas. The hypothesis is that an injection of Cl histolyticum purified collagenase (enzyme) will cause a rapid and durable reduction in size of canine lipomas. We are currently enrolling dogs with moderate sized lipomas as candidates. Inclusion criteria are tumors that are approximately 2-6 centimeters in diameter with essentially healthy dogs. The study is non-invasive and requires three to four follow-up visits. Results from a dose escalation and Phase I trial indicate very positive results with more that 90% of the patients achieving a reduction in lipoma size of at least 50% with a single injection. Side effects noted in these studies were trivial; the drug is FDA approved for use in humans with over 11,000 people already having been injected with the drug to date. Interested candidates can be enrolled by contacting the study site coordinator Jannete at .
CARLSBAD, Calif. -- A canine cancer facility in Carlsbad is conducting a new study that could potentially be a game-changer when it comes to treating pets and eventually humans. “It has not been done,” said Oncologist and Internist Dr. Greg Ogilvie who is also Director of the Angel Care Cancer Center. “It’s a new area of research that is exciting and we hope will develop not only benefits for animals with cancer but also people.”
Inclusion Criteria: Clinically healthy dogs with palpable, measurable cyto- or histologically confirmed malignancy and acceptable recent chest radiographs and blood work. Study will cover costs of each drug signal therapy delivered by a device that is placed over the palpable 1-6 cm tumor and all in-hospital rechecks and restaging at CVS.
Inclusion Criteria: Clinically healthy dogs with stage III/IVa cyto- or histologically confirmed intermediate or large cell B cell lymphoma and acceptable recent chest radiographs and blood work. Study will cover costs of flow cytometry, an abbreviated CHOP therapy +/- monoclonal antibody treatment plus weekly in-hospital rechecks and restagings at CVS.
A few weeks back, a black-and-white terrier mix named Chance entered a clinical trial for a drug that may offer a completely new way to combat cancer—not only in dogs, but in people, too. The drug, made by San Diego-based Genelux, uses a genetically engineered virus to annihilate tumor cells. Genelux made two different versions of the drug and is now testing one in people and other in dogs, as part of a wide-ranging research strategy designed to yield cutting-edge cancer treatments for both man and man’s best friend. Why dogs? “Cancer as a
Dr. Ogilvie is directing a ground breaking canine clinical trial using a new and revolutionary non-invasive medical device called Voyager. "Voyager is just beginning its voyage as we are beginning the process of identifying the cancers its most effective to treat. It seems to have a broad spectrum of efficacy while being quite safe." The Voyager results are remarkable. Rapid and durable tumor response has been seen in many patients, resulting in partial and complete remissions. After one week of treatment, Voyager safely eliminated 90% of one..
